Detalhe da pesquisa
1.
Pervasive chromosomal instability and karyotype order in tumour evolution.
Nature
; 587(7832): 126-132, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32879494
2.
Pan-cancer whole-genome analyses of metastatic solid tumours.
Nature
; 575(7781): 210-216, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31645765
3.
Analytical Validation of a Volumetric Absorptive Microsampling Method for Therapeutic Drug Monitoring of the Oral Targeted Anticancer Agents, Abiraterone, Alectinib, Cabozantinib, Imatinib, Olaparib, and Sunitinib, and Metabolites.
Ther Drug Monit
; 2024 Jan 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38321598
4.
Clinical Relevance of High Plasma Trough Levels of the Kinase Inhibitors Crizotinib, Alectinib, Osimertinib, Dabrafenib, and Trametinib in NSCLC Patients.
Ther Drug Monit
; 46(1): 73-79, 2024 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37348074
5.
Referral patterns of GIST patients: data from a nationwide study.
Acta Oncol
; 63: 28-34, 2024 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38353407
6.
Financial difficulties experienced by patients with gastrointestinal stromal tumours (GIST) in the Netherlands: data from a cross-sectional multicentre study.
Support Care Cancer
; 32(5): 279, 2024 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38594390
7.
Phase Ib/II Study of the Efficacy and Safety of Binimetinib (MEK162) Plus Panitumumab for Mutant or Wild-Type RAS Metastatic Colorectal Cancer.
Oncologist
; 28(12): e1209-e1218, 2023 Dec 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37597246
8.
Neoadjuvant Imatinib in Locally Advanced Gastrointestinal Stromal Tumors (GISTs) is Effective and Safe: Results from a Prospective Single-Center Study with 108 Patients.
Ann Surg Oncol
; 30(13): 8660-8668, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37814179
9.
A phase 1 open-label study to assess the relative bioavailability of TAK-931 tablets in reference to powder-in-capsule in patients with advanced solid tumors.
Invest New Drugs
; 41(1): 53-59, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36409435
10.
WEE1 inhibitor adavosertib in combination with carboplatin in advanced TP53 mutated ovarian cancer: A biomarker-enriched phase II study.
Gynecol Oncol
; 174: 239-246, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37236033
11.
Optimizing carboplatin dosing by an improved prediction of carboplatin clearance using a CT-enhanced estimate of renal function.
Br J Clin Pharmacol
; 89(10): 3016-3025, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37194167
12.
Exposure-Response Analyses of Olaparib in Real-Life Patients with Ovarian Cancer.
Pharm Res
; 40(5): 1239-1247, 2023 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-36944815
13.
The association of having a monitoring or blunting coping style with psychological distress, health-related quality of life and satisfaction with healthcare in gastrointestinal stromal tumour (GIST) patients.
Acta Oncol
; 62(12): 1616-1624, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37856077
14.
The QT interval prolongation potential of anticancer and supportive drugs: a comprehensive overview.
Lancet Oncol
; 23(9): e406-e415, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36055309
15.
First-in-human phase 1 dose-escalation study of CAN04, a first-in-class interleukin-1 receptor accessory protein (IL1RAP) antibody in patients with solid tumours.
Br J Cancer
; 126(7): 1010-1017, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34903842
16.
Encorafenib, Binimetinib, and Cetuximab in BRAF V600E-Mutated Colorectal Cancer.
N Engl J Med
; 381(17): 1632-1643, 2019 10 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31566309
17.
Exposure-response analyses of cabozantinib in patients with metastatic renal cell cancer.
BMC Cancer
; 22(1): 228, 2022 Mar 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35236333
18.
Healthy volunteers in first-in-human oncology drug development for small molecules.
Br J Clin Pharmacol
; 88(4): 1773-1784, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34558113
19.
Ritonavir-Boosted Exposure of Kinase Inhibitors: an Open Label, Cross-over Pharmacokinetic Proof-of-Concept Trial with Erlotinib.
Pharm Res
; 39(4): 669-676, 2022 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-35352280
20.
Exposure-Response Analysis of Osimertinib in EGFR Mutation Positive Non-Small Cell Lung Cancer Patients in a Real-Life Setting.
Pharm Res
; 39(10): 2507-2514, 2022 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-35978149